Carbon adsorbents for blood purification

Carol Howell (Inventor), Susan Sandeman (Inventor)

Research output: PatentResearch

Abstract

This invention relates to microporous/mesoporous or microporous/macroporous carbon and its use for the removal from blood of substances contrary to health. These include externally introduced toxins such as bacterially derived staphylococcus enterotoxins A, B, TSST-1 or autologous, biologically active molecules with harmful, systemic effects when their activity is excessive or unregulated. Examples include the removal of inappropriate amounts of pro- or anti-inflammatory molecules and toxic mediators of systemic inflammatory response syndrome related to sepsis, cardio-pulmonary by-pass surgery, ischaemic reperfusion injury; the removal of larger molecular weight and protein bound uremic and liver toxins related to chronic kidney and liver failure respectively, the removal of toxins relevant to biological and chemical warfare.
Original languageEnglish
Publication statusPublished - 16 Jun 2011

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Chemical Warfare
Biological Warfare
Systemic Inflammatory Response Syndrome
End Stage Liver Disease
Poisons
Reperfusion Injury
Chronic Kidney Failure
Sepsis
Anti-Inflammatory Agents
Carbon
Molecular Weight
Lung
Liver
Health
Proteins
staphylococcal enterotoxin B
Staphylococcal enterotoxin F

Cite this

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title = "Carbon adsorbents for blood purification",
abstract = "This invention relates to microporous/mesoporous or microporous/macroporous carbon and its use for the removal from blood of substances contrary to health. These include externally introduced toxins such as bacterially derived staphylococcus enterotoxins A, B, TSST-1 or autologous, biologically active molecules with harmful, systemic effects when their activity is excessive or unregulated. Examples include the removal of inappropriate amounts of pro- or anti-inflammatory molecules and toxic mediators of systemic inflammatory response syndrome related to sepsis, cardio-pulmonary by-pass surgery, ischaemic reperfusion injury; the removal of larger molecular weight and protein bound uremic and liver toxins related to chronic kidney and liver failure respectively, the removal of toxins relevant to biological and chemical warfare.",
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Carbon adsorbents for blood purification. / Howell, Carol (Inventor); Sandeman, Susan (Inventor).

Research output: PatentResearch

TY - PAT

T1 - Carbon adsorbents for blood purification

AU - Howell, Carol

AU - Sandeman, Susan

PY - 2011/6/16

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N2 - This invention relates to microporous/mesoporous or microporous/macroporous carbon and its use for the removal from blood of substances contrary to health. These include externally introduced toxins such as bacterially derived staphylococcus enterotoxins A, B, TSST-1 or autologous, biologically active molecules with harmful, systemic effects when their activity is excessive or unregulated. Examples include the removal of inappropriate amounts of pro- or anti-inflammatory molecules and toxic mediators of systemic inflammatory response syndrome related to sepsis, cardio-pulmonary by-pass surgery, ischaemic reperfusion injury; the removal of larger molecular weight and protein bound uremic and liver toxins related to chronic kidney and liver failure respectively, the removal of toxins relevant to biological and chemical warfare.

AB - This invention relates to microporous/mesoporous or microporous/macroporous carbon and its use for the removal from blood of substances contrary to health. These include externally introduced toxins such as bacterially derived staphylococcus enterotoxins A, B, TSST-1 or autologous, biologically active molecules with harmful, systemic effects when their activity is excessive or unregulated. Examples include the removal of inappropriate amounts of pro- or anti-inflammatory molecules and toxic mediators of systemic inflammatory response syndrome related to sepsis, cardio-pulmonary by-pass surgery, ischaemic reperfusion injury; the removal of larger molecular weight and protein bound uremic and liver toxins related to chronic kidney and liver failure respectively, the removal of toxins relevant to biological and chemical warfare.

M3 - Patent

ER -

Howell C, Sandeman S, inventors. Carbon adsorbents for blood purification. 2011 Jun 16.