Annelation of perfluorinated heteroaromatic systems by 1,3-dicarbonyl derivatives

Matthew W. Cartwright, Emma L. Parks, Graham Pattison, Rachel Slater, Graham Sandford, Ian Wilson, Dmitrii S. Yufit, Judith A.K. Howard, John A. Christopher, David D. Miller

Research output: Contribution to journalArticle

Abstract

Reactions of various perfluorinated heteroaromatic substrates such as tetrafluoro-4-cyanopyridine, tetrafluoropyrazine and tetrafluoropyridazine with 1,3-dicarbonyl systems gave corresponding [5,6]-ring fused furo derivatives. Subsequent reactions of the [5,6] bicyclic scaffolds with nucleophiles gave some highly functionalised heteroaromatic systems.

Original languageEnglish
Pages (from-to)3222-3227
Number of pages6
JournalTetrahedron
Volume66
Issue number17
DOIs
Publication statusPublished - 24 Apr 2010

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    Cartwright, M. W., Parks, E. L., Pattison, G., Slater, R., Sandford, G., Wilson, I., Yufit, D. S., Howard, J. A. K., Christopher, J. A., & Miller, D. D. (2010). Annelation of perfluorinated heteroaromatic systems by 1,3-dicarbonyl derivatives. Tetrahedron, 66(17), 3222-3227. https://doi.org/10.1016/j.tet.2010.02.083