Annelation of perfluorinated heteroaromatic systems by 1,3-dicarbonyl derivatives

Matthew W. Cartwright, Emma L. Parks, Graham Pattison, Rachel Slater, Graham Sandford, Ian Wilson, Dmitrii S. Yufit, Judith A.K. Howard, John A. Christopher, David D. Miller

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Reactions of various perfluorinated heteroaromatic substrates such as tetrafluoro-4-cyanopyridine, tetrafluoropyrazine and tetrafluoropyridazine with 1,3-dicarbonyl systems gave corresponding [5,6]-ring fused furo derivatives. Subsequent reactions of the [5,6] bicyclic scaffolds with nucleophiles gave some highly functionalised heteroaromatic systems.

    Original languageEnglish
    Pages (from-to)3222-3227
    Number of pages6
    JournalTetrahedron
    Volume66
    Issue number17
    DOIs
    Publication statusPublished - 24 Apr 2010

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