TY - JOUR
T1 - Adsorbed pluronics on the skin of human volunteers: effects on bacterial adhesion
AU - Marsh, L.H.
AU - Alexander, C.
AU - Coke, M.
AU - Dettmar, P.W.
AU - Havler, M.
AU - Nevell, T.G.
AU - Smart, John
AU - Timmins, B.
AU - Tsibouklis, J.
PY - 2003/1
Y1 - 2003/1
N2 - An amphiphilic copolymer, Pluronic F127, has been deposited, by adsorption, to the skin of human volunteers and the ability of the coated skin to resist bacterial colonisation has been evaluated. In parallel, the ability of the same copolymer to act as a bacterial release agent has been evaluated. In both cases, F127 proved to be of little added value in formulations designed to suppress the bacterial colonisation of human skin.
AB - An amphiphilic copolymer, Pluronic F127, has been deposited, by adsorption, to the skin of human volunteers and the ability of the coated skin to resist bacterial colonisation has been evaluated. In parallel, the ability of the same copolymer to act as a bacterial release agent has been evaluated. In both cases, F127 proved to be of little added value in formulations designed to suppress the bacterial colonisation of human skin.
KW - Bacterial-release coatings
KW - Pluronic F127
KW - In vivo evaluation
U2 - 10.1016/S0378-5173(02)00592-6
DO - 10.1016/S0378-5173(02)00592-6
M3 - Article
SN - 1873-3476
VL - 251
SP - 155
EP - 163
JO - International Journal of Pharmaceutics
JF - International Journal of Pharmaceutics
IS - 1-2
ER -