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Absence of premature senescence in Werner's syndrome keratinocytes
B. Ibrahim
,
Angela Sheerin
, Katrin Jennert-Burston
, Joe L.E. Bird
, M.V. Massala
, Matthew Illsley
, S.Elizabeth James
,
Richard Faragher
University of Brighton
Research output
:
Contribution to journal
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›
peer-review
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Keyphrases
Werner Syndrome
100%
Keratinocytes
100%
Premature Senescence
100%
Fibroblasts
22%
Population Doubling Time
22%
Fibroblast Culture
22%
Autosomal Recessive
11%
Cellular Level
11%
Loss Function
11%
Premature Aging
11%
Gain-of-function mutation
11%
Telomerase Activity
11%
Replication Fork Stalling
11%
Replicative Lifespan
11%
Cellular Senescence
11%
Epidermis
11%
Causal Mechanisms
11%
Growth Rate
11%
Stem Cells
11%
Human Fibroblasts
11%
In Vivo Aging
11%
Mechanism-based
11%
Attrition
11%
Slow Growth
11%
Senescence Phenotype
11%
Growth Feature
11%
Tissue Type
11%
Segmental Progeroid Syndromes
11%
Mammalian Aging
11%
Growth Arrest
11%
Holoclone
11%
Expression Activity
11%
Recessive Genetic Disorder
11%
P63 Expression
11%
Medicine and Dentistry
Prematurity
100%
Werner Syndrome
100%
Keratinocyte
100%
Fibroblast
44%
In Vitro
11%
Telomerase
11%
Genetic Disorder
11%
Lifespan
11%
Progeroid Syndromes
11%
Protein P53
11%
Loss of Function Mutation
11%
Karyotype
11%
Tissue (Anatomy)
11%
Autosomal Recessive Inheritance
11%
Growth Disorder
11%
Cellular Senescence
11%
P16
11%
Premature Aging
11%
Stem Cell
11%
Biochemistry, Genetics and Molecular Biology
Werner Syndrome
100%
Keratinocyte
100%
Wild Type
22%
Fibroblast Culture
22%
Fibroblast
22%
Telomerase
11%
P53
11%
Lifespan
11%
P16
11%
Genetic Disorder
11%
Loss of Function Mutation
11%
Stem Cell
11%
Karyotype
11%
Autosomal Recessive Inheritance
11%
Pharmacology, Toxicology and Pharmaceutical Science
Prematurity
100%
Werner Syndrome
100%
Telomerase
11%
Protein P53
11%
Growth Disorder
11%
Syndrome
11%
Premature Aging
11%
Genetic Disorder
11%
Agricultural and Biological Sciences
Keratinocyte
100%
Fibroblast
80%
Progenitor Cell
20%
Telomerase
20%
Loss-of-Function Mutation
20%
Cellular Senescence
20%