@inbook{b299548a9c7c42118c3d974f1347ce85,
title = "A novel skin substitute biomaterial to treat full-thickness wounds in a burns emergency care",
abstract = "A novel porcine collagen-based paste dermal substitute to treat full-thickness wounds has been investigated. A thin split-thickness skin graft or autologous cultured keratinocytes have been combined with dermal replacement biomaterial and applied to full-thickness wounds in a porcine wound chamber preclinical experimental model. The data obtained suggest that: (1) dermal substitute biomaterials may improve wound re-epithelialisation when combined with cultured autologous keratinocytes and (2) porcine collagen paste is able to support split-thickness skin graft survival as well as autologous cultured keratinocyte proliferation. These results demonstrate that the novel porcine collagen paste has a potential as a dermal substitute to treat acute full-thickness wounds and an application for the burns emergency care treatment.",
keywords = "Permacol, Integra, Skin substitute, Dermal substitute, Cultured keratinocytes, Collagen, Animal model",
author = "Rostislav Shevchenko and P.D. Sibbons and J.R. Sharpe and S.Elizabeth James",
year = "2011",
month = dec,
day = "31",
doi = "10.1007/978-94-007-0217-2_25",
language = "English",
isbn = "9789400702165",
series = "NATO Science for Peace and Security Series A: Chemistry and Biology",
publisher = "Springer",
pages = "247--255",
editor = "S. Mikhalovsky and A. Khajibaev",
booktitle = "Biodefence: advanced materials and methods for health protection",
}