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A method for simulating the growth of cells on a general surface using the finite element method

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Abstract

The growth of cells on a surface coated with a nutrient is a technique widely used for tissue regeneration. A system of reaction–diffusion equations is used to model the densities of both the cells and the nutrient. This paper presents a finite element method for solving the equations on a general surface which is approximated by a set of flat triangular elements. A change of variables is used to convert the diffusion equations expressed in local coordinates on each element into the equivalent equation expressed in terms of the global coordinates. The methods are illustrated with some typical examples.
Original languageEnglish
Number of pages12
JournalComputer Methods in Biomechanics and Biomedical Engineering
DOIs
Publication statusPublished - 15 Mar 2026

Bibliographical note

Publisher Copyright:
© 2026 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

Keywords

  • Cell growth
  • finite elements
  • general surface
  • reaction-diffusion equation
  • surface diffusion

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