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• 2020

  Emilin 2 promotes the mechanical gradient of the cochlear basilar membrane and resolution of frequencies in sound

  Russell, I. J., Lukashkina, V. A., Levic, S., Cho, Y. W., Lukashkin, A. N., Ng, L. & Forrest, D., 10 Jun 2020, In: Science Advances. 6, 24, eaba2634.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • elastin microfibril interface located protein
  • Basilar Membrane
  • Cochlea
  • Extracellular Matrix Proteins

• Local Drug Delivery to the Entire Cochlea without Breaching Its Boundaries

  Lukashkin, A. N., Sadreev, I. I., Zakharova, N., Russell, I. J. & Yarin, Y. M., 26 Feb 2020, In: iScience. 23, 3, 100945.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Cochlea
  • Pharmaceutical Preparations
  • Inner Ear
  • Stapes
  • Middle Ear
• 2019

  Drug Diffusion Along an Intact Mammalian Cochlea

  Sadreev, I. I., Burwood, G. W. S., Flaherty, S. M., Kim, J., Russell, I. J., Abdullin, T. I. & Lukashkin, A. N., 26 Apr 2019, In: Frontiers in Cellular Neuroscience. 13, p. 1-11 11 p., 161.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Cochlea
  • Salicylates
  • Pharmaceutical Preparations
  • Perilymph
  • Membranes
• 2018

  Roles for gap-junctions in cochlear amplification and micromechanics exposed by a conexin 30 mutation

  Lukashkina, V. A., Levic, S., Strenzke, N., Lukashkin, A. N. & Russell, I. J., 31 May 2018, To the Ear and Back Again - Advances in Auditory Biophysics: Proceedings of the 13th Mechanics of Hearing Workshop. American Institute of Physics Inc., Vol. 1965. 100001. (AIP Conference Proceedings; vol. 1965, no. 1).

  Research output: Chapter in Book/Conference proceeding with ISSN or ISBN › Conference contribution with ISSN or ISBN › peer-review

  Open Access

  File

  • micromechanics
  • mutations
  • mice
  • hair
  • hearing

• Self-assembled nanoformulation of methylprednisolone succinatewith carboxylated block copolymer for local glucocorticoid therapy

  Kamalova, M. I., Ðang, T., Petrova, N. V., Laikov, A. V., Luong, D., Akhmadishina, R. A., Lukashkin, A. & Abdullin, T. I., 11 Jan 2018, In: Colloids and Surfaces B: Biointerfaces. 164, p. 78-88 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • glucocorticoids
  • block copolymers
  • micelles
  • therapy
  • propylene oxide

• The Mammalian Ear: Physics and the Principles of Evolution

  Manley, G., Lukashkin, A., Simoes, P., Burwood, G. & Russell, I., 1 Mar 2018, In: Acoustics Today. 14, 1, p. 8-16 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Natural Selection
  • Physical Laws
  • Ear
  • Physics

• Transgenic Tmc2 expression preserves inner ear hair cells and vestibular function in mice lacking Tmc1

  Asai, Y., Pan, B., Nist-Lund, C., Galvin, A., Lukashkin, A. N., Lukashkina, V. A., Chen, T., Zhou, W., Zhu, H., Russell, I. J., Holt, J. R. & Géléoc, G. S. G., 14 Aug 2018, In: Scientific Reports. 8, 1, p. 1-15 15 p., 12124.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Inner Auditory Hair Cells
  • Inner Ear
  • Vestibular Hair Cells
  • Proteins
  • Auditory Hair Cells
• 2017

  A connexin30 mutation rescues hearing and reveals roles for gap junctions in cochlear amplification and micromechanics

  Lukashkina, V., Levic, S., Lukashkin, A., Strenzke, N. & Russell, I., 21 Feb 2017, In: Nature Communications. 8, 14530.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

• Amplification mode differs along the length of the mouse cochlea as revealed by connexin 26 deletion from specific gap junctions

  Lukashkina, V., Yamashita, T., Zuo, J., Lukashkin, A. & Russell, I., 12 Jul 2017, In: Scientific Reports. 7, p. 1-11 11 p., 5185.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Connexin 26
  • Gap Junctions
  • Cochlea
  • Outer Auditory Hair Cells
  • Basilar Membrane

• Corrigendum: A connexin30 mutation rescues hearing and reveals roles for gap junctions in cochlear amplification and micromechanics

  Lukashkina, V. A., Levic, S., Lukashkin, A. N., Strenzke, N. & Russell, I. J., 21 Mar 2017, In: Nature Communications. 8, 1 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

• Rippling pattern of distortion product otoacoustic emissions evoked by high-frequency primaries in guinea pigs

  Burwood, G., Russell, I. & Lukashkin, A., 11 Aug 2017, In: Journal of the Acoustical Society of America. 142, 2, p. 855-862 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • pig
  • product
  • ripple
  • standing wave
  • oscillation
• 2016

  Cochlear excitation by the near-field component during stimulation through the partially occluded round window

  Weddell, T. D., Yarin, Y. M., Drexl, M., Russell, I. J., Elliott, S. J. & Lukashkin, A. N., 15 Jan 2016, Mechanics of Hearing: Protein to Perception - Proceedings of the 12th International Workshop on the Mechanics of Hearing. American Institute of Physics Inc., Vol. 1703. 060019

  Research output: Chapter in Book/Conference proceeding with ISSN or ISBN › Conference contribution with ISSN or ISBN › peer-review

  • stimulation
  • near fields
  • cochlea
  • membranes
  • excitation

• Efficient energy transmission and amplification in the cochlea relies on frequency-dependent material properties of the tectorial membrane

  Jones, G. P., Lukashkina, V. A., Russell, I. J., Elliott, S. J. & Lukashkin, A. N., 15 Jan 2016, Mechanics of Hearing: Protein to Perception - Proceedings of the 12th International Workshop on the Mechanics of Hearing. American Institute of Physics Inc., Vol. 1703. 080002

  Research output: Chapter in Book/Conference proceeding with ISSN or ISBN › Conference contribution with ISSN or ISBN › peer-review

  • cochlea
  • membranes
  • energy
  • traveling waves
  • stiffness
• 2015

  Modified Protein Expression in the Tectorial Membrane of the Cochlea Reveals Roles for the Striated Sheet Matrix

  Jones, G., Elliott, S., Russell, I. & Lukashkin, A., 6 Jan 2015, In: Biophysical Journal. 108, 1, p. 203-210 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Tectorial Membrane
  • Cochlea
  • Outer Auditory Hair Cells
  • Proteins
  • Static Electricity
• 2014

  A novel mechanism of cochlear excitation during simultaneous stimulation and pressure relief through the round window

  Weddell, T., Yarin, Y. M., Drexl, M., Russell, I., Elliott, S. J. & Lukashkin, A., 6 Apr 2014, In: Interface. 11, 93, p. 1-10 10 p.

  Research output: Contribution to journal › Article › peer-review

• Multiple indices of the 'bounce' phenomenon obtained from the same human ears

  Drexl, M., Ueberfuhr, M., Weddell, T., Lukashkin, A., Wiegrebe, L., Krause, E. & Guerkov, R., 28 Feb 2014, In: Journal of the Association for Research in Otolaryngology. 15, 1, p. 57-72 16 p.

  Research output: Contribution to journal › Article › peer-review

• Tonotopic morphometry of the lamina reticularis of the guinea pig cochlea with associated microstructures and related mechanical implications

  Yarin, Y. M., Lukashkin, A., Poznyakovskiy, A. A., Meissner, H., Fleischer, M., Baumgart, J., Richter, C., Kuhlisch, E. & Zahnert, T., 28 Feb 2014, In: Journal of the Association for Research in Otolaryngology. 15, 1, p. 1-11 11 p.

  Research output: Contribution to journal › Article › peer-review

• 2013

  Frequency-dependent properties of the tectorial membrane facilitate energy transmission and amplification in the cochlea

  Jones, G. P., Lukashkina, V., Russell, I., Elliott, S. J. & Lukashkin, A., 19 Mar 2013, In: Biophysical Journal. 104, 6, p. 1357-1366 10 p.

  Research output: Contribution to journal › Article › peer-review

  • amplification
  • membrane
  • energy
  • stiffness
  • loss
• 2012

  A mouse model for human deafness DFNB22 reveals that hearing impairment is due to a loss of inner hair cell stimulation

  Lukashkin, A., Legan, P. K., Weddell, T., Lukashkina, V., Goodyear, R. J., Welstead, L. J., Petit, C., Russell, I. & Richardson, G. P., 20 Nov 2012, In: Proceedings of the National Academy of Sciences. 109, 47, p. 19351-19356 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Autosomal Recessive 22 Deafness
  • Tectorial Membrane
  • Inner Auditory Hair Cells
  • Organ of Corti
  • Deafness