2019
Oxytosin as a novel antidegenerative?
Faragher, R. G. A., 1 Jan 2019, (Accepted/In press) In : British Journal of Dermatology. 181, 6, p. 1122-1123 2 p.Research output: Contribution to journal › Article
Population type influences the rate of ageing
Overall, A. & Faragher, R., 8 Feb 2019, In : Heredity. 123, 2, p. 273-282 10 p.Research output: Contribution to journal › Article
Open Access
File
Population
Survival Rate
Genetic Drift
Population Density
Gene Frequency
2018
FOXO1 and ETV6 genes may represent novel regulators of splicing factor expression in cellular senescence
Latorre, E., Ostler, E. L., Faragher, R. G. A. & Harries, L. W., 8 Aug 2018, In : The FASEB Journal.Research output: Contribution to journal › Article
Cell Aging
MAP Kinase Signaling System
Genes
Fibroblasts
Gene Knockdown Techniques
Obesity and type-2 diabetes as inducers of premature cellular senescence and ageing
Burton, D. G. A. & Faragher, R. G. A., 27 Jul 2018, In : Biogerontology. 19, 6, p. 447–459Research output: Contribution to journal › Article
Open Access
File
Cell Aging
Type 2 Diabetes Mellitus
Obesity
Kidney Diseases
Cardiovascular Diseases
Telomere elongation through hTERT immortalization leads to chromosome repositioning in control cells and genomic instability in Hutchinson-Gilford progeria syndrome fibroblasts, expressing a novel SUN1 isoform
Bikkul, M. U., Faragher, R. G. A., Worthington, G., Meinke, P., Kerr, A. R. W., Sammy, A., Riyahi, K., Horton, D., Schirmer, E. C., Hubank, M., Kill, I. R., Anderson, R. M., Slijepcevic, P., Makarov, E. & Bridger, J. M., 26 Nov 2018, In : Genes Chromosomes and Cancer. 58, 6, p. 341-356Research output: Contribution to journal › Article
Open Access
File
Progeria
Genomic Instability
Telomere
Protein Isoforms
Fibroblasts
2017
Senescence in the aging process
Faragher, R., McArdle, A., Willows, A. & Ostler, E., 25 Jul 2017, In : F1000 Research. 6Research output: Contribution to journal › Article
Open Access
File
Phenotype
Transcriptome
Small molecule modulation of splicing factor expression is associated with rescue from cellular senescence
Latorre, E., Birar, V., Sheerin, A., Jeynes, C. C., Hooper, A., Dawe, H., Melzer, D., Cox, L., Faragher, R., Ostler, E. & Harries, L. W., 17 Oct 2017, In : BMC Cell Biology. 18Research output: Contribution to journal › Article
Open Access
File
Cell Aging
Cell Cycle
Messenger RNA
Telomere
Fibroblasts
2016
Absence of premature senescence in Werner's syndrome keratinocytes
Ibrahim, B., Sheerin, A., Jennert-Burston, K., Bird, J. L. E., Massala, M. V., Illsley, M., James, S. E. & Faragher, R., 2 Aug 2016, In : Experimental Gerontology. 83, p. 139-147 9 p.Research output: Contribution to journal › Article
Open Access
File
Werner Syndrome
Keratinocytes
Fibroblasts
Cell Aging
Premature Aging
2015
A facile, stereoselective, one-pot synthesis of resveratrol derivatives
Birar, V., Sheerin, A., Milkovicova, J., Faragher, R. & Ostler, E., 20 May 2015, In : Chemistry Central Journal. 9Research output: Contribution to journal › Article
Open Access
File
Derivatives
Stilbenes
Electrons
Purification
Anti-Inflammatory Agents
Cellular senescence: from growth arrest to immunogenic conversion
Burton, D. G. A. & Faragher, R. G. A., 1 Apr 2015, In : Age. 37, 2, p. 1-19 19 p.Research output: Contribution to journal › Article
Cell Aging
Fibroblasts
DNA Damage
Growth
Ligands
Preparing for an Aging World: Engaging Biogerontologists, Geriatricians, and the Society
Nikolich-Žugich, J., Goldman, D. P., Cohen, P. R., Cortese, D., Fontana, L., Kennedy, B. K., Mohler, M. J., Olshansky, S. J., Perls, T., Perry, D., Richardson, A., Ritchie, C., Wertheimer, A. M., Faragher, R. & Fain, M. J., 29 Sep 2015, In : Journals of Gerontology, Series A. 71, 4, p. 435-444 10 p.Research output: Contribution to journal › Article
Medicare
Health Expenditures
Quality of Life
Demography
Education
Should we treat aging as a disease? The consequences and dangers of miscategorisation
Faragher, R., 14 Jul 2015, In : Frontiers in Genetics. 6, p. 171-178 8 p.Research output: Contribution to journal › Article
Open Access
File
Disease
evidence
consciousness
money
scenario
Suppression of the senescence-associated secretory phenotype (SASP) in human fibroblasts using small molecule inhibitors of p38 MAP kinase and MK2
Alimbetov, D., Davis, T., Brook, A. J. C., Cox, L., Faragher, R., Nurgozhin, T., Zhumadilov, Z. & Kipling, D., 23 Sep 2015, In : Biogerontology. 17, 2, p. 305-315 11 p.Research output: Contribution to journal › Article
Open Access
File
p38 Mitogen-Activated Protein Kinases
Fibroblasts
Phenotype
Secretory Component
Phase III Clinical Trials
2014
Better immunity in later life: A position paper
Faragher, R., Frasca, D., Remarque, E. & Pawelec, G., 1 Jan 2014, In : Age. 36, 3, p. 1041-1048 8 p.Research output: Contribution to journal › Article
Immunity
Immune System
Quality of Life
Delivery of Health Care
Education
2013
Biomarkers, interventions and healthy ageing
Kenessary, A., Zhumadilov, Z., Nurgozhin, T., Kipling, D., Yeoman, M., Cox, L., Ostler, E. & Faragher, R., 25 May 2013, In : New Biotechnology. 30, 4, p. 373-377 5 p.Research output: Contribution to journal › Article
Biomarkers
Aging of materials
Morbidity
Quality of Life
Pathology
2012
Characterization of cellular senescence mechanisms in human corneal endothelial cells
Sheerin, A., Smith, S. K., Jennert-Burston, K., Brook, A. J., Allen, M., Ibrahim, B., Jones, D. L., Wallis, C., Engelmann, K., Rhys-Williams, W., Faragher, R. & Kipling, D., Apr 2012, In : Aging Cell. 11, 2, p. 234-240 7 p.Research output: Contribution to journal › Article
Editorial: a systematic end to "muddling through"?
Faragher, R. (ed.) & Ostler, E. (ed.), 28 Feb 2012, UK: Springer-Verlag. 2 p.Research output: Book/Report › Book - edited
Insights into CNS ageing from animal models of senescence
Yeoman, M., Scutt, G. & Faragher, R., 30 Jun 2012, In : Nature Reviews Neuroscience. 13, 6, p. 435-445 11 p.Research output: Contribution to journal › Article
Recapitulation of Werner syndrome sensitivity to camptothecin by limited knockdown of the WRN helicase/exonuclease
Bird, J. L. E., Jennert-Burston, K., Bacheler, M. A., Mason, P. A., Lowe, J. E., Heo, S. J., Campisi, J., Faragher, R. & Cox, L. S., 28 Feb 2012, In : Biogerontology. 13, 1Research output: Contribution to journal › Article
Werner Syndrome
Camptothecin
Exonucleases
Topoisomerase Inhibitors
Fibroblasts
2011
Chemical analysis of aging: testing predictions from green theory
Ostler, E., Iqbal, A., Faragher, R., Naughton, D., Piper, M. & Partridge, L., 2011, p. 64.Research output: Contribution to conference › Abstract
File
Drosophila melanogaster
Genetic Engineering
Diptera
Drosophila
Resveratrol, but not dihydroresveratrol, induces premature senescence in primary human fibroblasts
Faragher, R., Burton, D., Majecha, P., Fong, N. S., Davis, T., Sheerin, A. & Ostler, E., 12 Feb 2011, In : Age. 33, 4, p. 555-564 10 p.Research output: Contribution to journal › Article