9,10-Dioxa-1,2-diaza-anthracene derivatives from tetrafluoropyridazine

Graham Pattison; Graham Sandford; Dmitrii S. Yufit; Judith A K Howard; John A. Christopher; David D. Miller

doi:10.3762/bjoc.6.45

9,10-Dioxa-1,2-diaza-anthracene derivatives from tetrafluoropyridazine

Graham Pattison
, Graham Sandford
, Dmitrii S. Yufit
, Judith A K Howard
, John A. Christopher
, David D. Miller

Research output: Contribution to journal › Article › peer-review

Abstract

Reaction of tetrafluoropyridazine with catechol gives a tricyclic 9,10-dioxa-1,2-diaza-anthracene system by a sequential nucleophilic aromatic substitution ring annelation process, further extending the use of perfluoroheteroaromatic derivatives for the synthesis of unusual polyfunctional heterocyclic architectures. The tricyclic scaffold reacts with amines and sodium ethoxide providing a short series of functional 9,10-dioxa-1,2-diaza-anthracene systems.

Original language	English
Article number	45
Journal	Beilstein Journal of Organic Chemistry
Volume	6
DOIs	https://doi.org/10.3762/bjoc.6.45
Publication status	Published - 6 May 2010

Keywords

9,10-dioxa-1,2-diaza-anthracene
Benzodioxinopyridazine
Heterocyclic synthesis
Nucleophilic aromatic substitution
Perfluoroheteroaromatic
Tetrafluoropyrazine

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title = "9,10-Dioxa-1,2-diaza-anthracene derivatives from tetrafluoropyridazine",

abstract = "Reaction of tetrafluoropyridazine with catechol gives a tricyclic 9,10-dioxa-1,2-diaza-anthracene system by a sequential nucleophilic aromatic substitution ring annelation process, further extending the use of perfluoroheteroaromatic derivatives for the synthesis of unusual polyfunctional heterocyclic architectures. The tricyclic scaffold reacts with amines and sodium ethoxide providing a short series of functional 9,10-dioxa-1,2-diaza-anthracene systems.",

keywords = "9,10-dioxa-1,2-diaza-anthracene, Benzodioxinopyridazine, Heterocyclic synthesis, Nucleophilic aromatic substitution, Perfluoroheteroaromatic, Tetrafluoropyrazine",

author = "Graham Pattison and Graham Sandford and Yufit, \{Dmitrii S.\} and Howard, \{Judith A K\} and Christopher, \{John A.\} and Miller, \{David D.\}",

year = "2010",

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doi = "10.3762/bjoc.6.45",

language = "English",

volume = "6",

journal = "Beilstein Journal of Organic Chemistry",

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TY - JOUR

T1 - 9,10-Dioxa-1,2-diaza-anthracene derivatives from tetrafluoropyridazine

AU - Pattison, Graham

AU - Sandford, Graham

AU - Yufit, Dmitrii S.

AU - Howard, Judith A K

AU - Christopher, John A.

AU - Miller, David D.

PY - 2010/5/6

Y1 - 2010/5/6

N2 - Reaction of tetrafluoropyridazine with catechol gives a tricyclic 9,10-dioxa-1,2-diaza-anthracene system by a sequential nucleophilic aromatic substitution ring annelation process, further extending the use of perfluoroheteroaromatic derivatives for the synthesis of unusual polyfunctional heterocyclic architectures. The tricyclic scaffold reacts with amines and sodium ethoxide providing a short series of functional 9,10-dioxa-1,2-diaza-anthracene systems.

AB - Reaction of tetrafluoropyridazine with catechol gives a tricyclic 9,10-dioxa-1,2-diaza-anthracene system by a sequential nucleophilic aromatic substitution ring annelation process, further extending the use of perfluoroheteroaromatic derivatives for the synthesis of unusual polyfunctional heterocyclic architectures. The tricyclic scaffold reacts with amines and sodium ethoxide providing a short series of functional 9,10-dioxa-1,2-diaza-anthracene systems.

KW - 9,10-dioxa-1,2-diaza-anthracene

KW - Benzodioxinopyridazine

KW - Heterocyclic synthesis

KW - Nucleophilic aromatic substitution

KW - Perfluoroheteroaromatic

KW - Tetrafluoropyrazine

UR - https://www.scopus.com/pages/publications/77952687805

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DO - 10.3762/bjoc.6.45

M3 - Article

AN - SCOPUS:77952687805

SN - 1860-5397

VL - 6

JO - Beilstein Journal of Organic Chemistry

JF - Beilstein Journal of Organic Chemistry

M1 - 45

ER -

9,10-Dioxa-1,2-diaza-anthracene derivatives from tetrafluoropyridazine

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Keywords

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