TY - JOUR
T1 - 9,10-Dioxa-1,2-diaza-anthracene derivatives from tetrafluoropyridazine
AU - Pattison, Graham
AU - Sandford, Graham
AU - Yufit, Dmitrii S.
AU - Howard, Judith A K
AU - Christopher, John A.
AU - Miller, David D.
PY - 2010/5/6
Y1 - 2010/5/6
N2 - Reaction of tetrafluoropyridazine with catechol gives a tricyclic 9,10-dioxa-1,2-diaza-anthracene system by a sequential nucleophilic aromatic substitution ring annelation process, further extending the use of perfluoroheteroaromatic derivatives for the synthesis of unusual polyfunctional heterocyclic architectures. The tricyclic scaffold reacts with amines and sodium ethoxide providing a short series of functional 9,10-dioxa-1,2-diaza-anthracene systems.
AB - Reaction of tetrafluoropyridazine with catechol gives a tricyclic 9,10-dioxa-1,2-diaza-anthracene system by a sequential nucleophilic aromatic substitution ring annelation process, further extending the use of perfluoroheteroaromatic derivatives for the synthesis of unusual polyfunctional heterocyclic architectures. The tricyclic scaffold reacts with amines and sodium ethoxide providing a short series of functional 9,10-dioxa-1,2-diaza-anthracene systems.
KW - 9,10-dioxa-1,2-diaza-anthracene
KW - Benzodioxinopyridazine
KW - Heterocyclic synthesis
KW - Nucleophilic aromatic substitution
KW - Perfluoroheteroaromatic
KW - Tetrafluoropyrazine
UR - http://www.scopus.com/inward/record.url?scp=77952687805&partnerID=8YFLogxK
U2 - 10.3762/bjoc.6.45
DO - 10.3762/bjoc.6.45
M3 - Article
AN - SCOPUS:77952687805
SN - 1860-5397
VL - 6
JO - Beilstein Journal of Organic Chemistry
JF - Beilstein Journal of Organic Chemistry
M1 - 45
ER -