Ion channels are transmembrane spanning proteins that allow the passage of ions from one side of the membrane to the other. These macromolecular proteins play critical roles in numerous physiological functions, such as controlling neuronal excitability. However, abnormal functioning of ion channels can cause disorders including epilepsy, cardiac arrhythmia, ataxia and cancer. My lab uses a multidisciplinary approach to understanding the molecular basis of, and developing therapies for, a spectrum of diseases arising from ion channel dysfunction. This includes research into elucidating the molecular mechanisms behind traditional herbal medicines, particularly the discovery of novel small molecule activators. Other interests include investigating the relationship between channel-transporter or “chansporter” interactions, and how these complexes can be influenced by the metabolic environment, and investigating fungal potassium channels as a strategy for future antifungal therapies.