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Research Output 1998 2019

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Abstract
2019

Off-target interactions as novel explantion of NSAID CV risk

Dolan, G., MacKenzie, L., Zloh, M. & Lione, L., Apr 2019.

Research output: Contribution to conferenceAbstractResearch

Open Access
File
Cardiovascular Agents
Anti-Inflammatory Agents
Diclofenac
Naproxen
Cytoplasmic and Nuclear Receptors

Regulation of pulmonary artery inflamation by PPARβ/δ

Perez Diaz, N., Lione, L., MacKenzie, L. & Hutter, V., Apr 2019.

Research output: Contribution to conferenceAbstractResearch

Open Access
File
PPAR delta
Pulmonary Artery
Inflammation
Transcription Factors
Anti-Inflammatory Agents
2018

Predicted interactions of selected NSAIDS with hERG potassium channel using Virtual Toxlab

Dolan, G., MacKenzie, L., Zloh, M. & Lione, L., Mar 2018.

Research output: Contribution to conferenceAbstractResearch

Open Access
File
Celecoxib
Potassium Channels
Anti-Inflammatory Agents
Cardiac Arrhythmias
etoricoxib
2017

Exploration of the structural differences between safe and unsafe NSAIDs using 3D molecular similarity

Dolan, G., MacKenzie, L. & Zloh, M., Dec 2017.

Research output: Contribution to conferenceAbstractResearchpeer-review

Open Access
File
etoricoxib
Naproxen
Anti-Inflammatory Agents
Pharmaceutical Preparations
Drug-Related Side Effects and Adverse Reactions

Identifying compounds that inhibit S100P – RAGE binding as a novel therapy for pancreatic cancer

Ogbeni, D., Camara, R., Chau, D., Patel, P., Kirton, S., MacKenzie, L. & Rossiter, S., 5 Jul 2017.

Research output: Contribution to conferenceAbstractResearchpeer-review

Open Access
File

Identifying inhibitor of S100P – RAGE binding as a novel therapy for pancreatic cancer

Ogbeni, D., Camara, R., Kirton, S., Patel, P., Crnogorac-Jurcevic, T., MacKenzie, L., Chau, D. & Rossiter, S., 5 Sep 2017.

Research output: Contribution to conferenceAbstractResearchpeer-review

Open Access
File

New Drugs for Pancreatic Cancer

Ogbeni, D., Chau, D., Patel, P., Rossiter, S. & MacKenzie, L., 13 Mar 2017.

Research output: Contribution to conferenceAbstractResearchpeer-review

Open Access
File
Pancreatic Neoplasms
Pharmaceutical Preparations
Neoplasms
Cell Movement
Adenocarcinoma

Novel compounds for the inhibition of S100P binding with RAGE as a potential therapy for pancreatic cancer

Ogbeni, D., Camara, R., Kirton, S., Crnogorac-Jurcevic, T., MacKenzie, L., Chau, D. & Rossiter, S., 5 Jul 2017.

Research output: Contribution to conferenceAbstractResearchpeer-review

Open Access
File
2016

Can NSAIDs alter Thyroid Hormone Function?

MacKenzie, L., 28 Sep 2016.

Research output: Contribution to conferenceAbstractResearch

Celecoxib
Thyroid Hormones
Anti-Inflammatory Agents
Diclofenac
Pharmaceutical Preparations
2015

ELISA screen of novel compounds that inhibit S100P and RAGE binding to identify new candidate drugs as a new therapy for pancreatic cancer

Ogbeni, D., Camara, R., Chau, D., Kirton, S., Rossiter, S. & MacKenzie, L., 2015.

Research output: Contribution to conferenceAbstractResearchpeer-review

Open Access
File
Pancreatic Neoplasms
Enzyme-Linked Immunosorbent Assay
Pharmaceutical Preparations
Therapeutics
Adenocarcinoma

Evidence that Diclofenac and Celecoxib are Thyroid Hormone Receptor Beta Antagonists; use of in silico, Molecular and Pharmacological Techniques

Perez Diaz, N., Zloh, M., Patel, P. & MacKenzie, L., Dec 2015.

Research output: Contribution to conferenceAbstractResearchpeer-review

Open Access
File
Celecoxib
Thyroid Hormone Receptors beta
Diclofenac
Non-Steroidal Anti-Inflammatory Agents
Computer Simulation

Identification of novel compounds that inhibit S100P and RAGE binding as a new therapy for Pancreatic Cancer

MacKenzie, L., 24 Aug 2015.

Research output: Contribution to conferenceAbstractResearch

Open Access
File
Pancreatic Neoplasms
Calcium-Binding Proteins
Neoplasm Metastasis
Neoplasms
Therapeutics

Targeting PPARbeta/delta in lung disease

MacKenzie, L., 1 Dec 2015.

Research output: Contribution to conferenceAbstractResearch