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Personal profile

Research interests

David Timson is a protein biochemist.  His research focuses on understanding how the structures of proteins influence their functions, with particular relevance to those proteins implicated in human disease and in biotechnology.  Current research areas include:

1.  Proteins of human galactose metabolism and how they are affected by the inherited metabolic disease, galactosemia.

2.  Calcium binding proteins and metabolic enzymes from helminth parasites.

3.  Quinone oxidoreductases

4.  Stress mitigation in biofuel production

5.  The biochemistry underlying fetal alcohol specturm disorders (collaboration led by Prof Paul Gard)

Education/Academic qualification

Queen's University Belfast

PhD, University of Birmingham

Bachelor, University of Birmingham

External positions

Editorial Board, Fermentation

Associate Editor, Biosceince Reports

Associate Editor, RSC Advances, Royal Society of Chemistry

Keywords

  • Q Science (General)
  • Biochemistry
  • Molecular Biology
  • Proteins
  • Enzymology

Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 2 Similar Profiles
Galactokinase Medicine & Life Sciences
Galactosemias Medicine & Life Sciences
Galactose Medicine & Life Sciences
Fasciola hepatica Medicine & Life Sciences
UDPglucose 4-Epimerase Medicine & Life Sciences
Enzymes Medicine & Life Sciences
Proteins Medicine & Life Sciences
Calmodulin Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2007 2019

NAD(P)H quinone oxidoreductase (NQO1): An enzyme which needs just enough mobility, in just the right places

Pey, A. L., Megarity, C. F. & Timson, D. J. 3 Jan 2019 39, 1, BSR20180459

Research output: Contribution to journalArticle

Open Access
File
Flavin-Adenine Dinucleotide
NAD
Oxidoreductases
Dicumarol
Quinones

A galactokinase-like protein from the liver fluke Fasciola hepatica

Zinsser, V. L., Cox, C., McAuley, M., Hoey, E. M., Trudgett, A. & Timson, D. J. 21 Jul 2018 192, p. 65-72 8 p.

Research output: Contribution to journalArticle

Galactokinase
Fasciola hepatica
Galactose
Acetylgalactosamine
Proteins
Schistosoma mansoni
Calmodulin
Calcium Channels
Calcium
Ions

Improving the activity and stability of human galactokinase for therapeutic and biotechnological applications

McAuley, M., Mesa-Torres, N., McFall, A., Morris, S., Huang, M., Pey, A. L. & Timson, D. 26 Apr 2018 19, 10, p. 1088-1095 8 p.

Research output: Contribution to journalArticle

Galactokinase
Human Activities
Enzyme Replacement Therapy
Enzymes
Galactosemias

Modulation of the mobility of a key region in human galactokinase: Impacts on catalysis and stability

McAuley, M., Huang, M. & Timson, D. J. 19 Sep 2018 81, p. 649-657 9 p.

Research output: Contribution to journalArticle

Galactokinase
Catalysis
Enzymes
Galactose
Catalytic Domain

Activities 2004 2017

  • 6 Membership of professional body
  • 1 Research degree
  • 1 Personal board membership of professional/academic bodies
  • 1 Visiting an external academic institution

PhD external examination

Timson, D. (Examiner)
2017

Activity: Research degree

Higher Education Academy, UK (External organisation)

Timson, D. (Chair)
2017 → …

Activity: Membership of professional body

Royal Society of Chemistry (External organisation)

Timson, D. (Chair)
2016 → …

Activity: Membership of professional body

Queen's University Belfast

Timson, D. (Visiting researcher)
20152018

Activity: Visiting an external academic institution

Biochemical Society (External organisation)

Timson, D. (Chair)
20132016

Activity: Personal board membership of professional/academic bodies