Research Output per year
Personal profile
Research interests
David Timson is a protein biochemist. His research focuses on understanding how the structures of proteins influence their functions, with particular relevance to those proteins implicated in human disease and in biotechnology. Current research areas include:
1. Proteins of human galactose metabolism and how they are affected by the inherited metabolic disease, galactosemia.
2. Calcium binding proteins and metabolic enzymes from helminth parasites.
3. Quinone oxidoreductases
4. Stress mitigation in biofuel production
5. The biochemistry underlying fetal alcohol specturm disorders (collaboration led by Prof Paul Gard)
Education/Academic qualification
Queen's University Belfast
PhD, University of Birmingham
Bachelor, University of Birmingham
External positions
Editorial Board, Fermentation
Associate Editor, Biosceince Reports
Associate Editor, RSC Advances, Royal Society of Chemistry
Keywords
- Q Science (General)
- Biochemistry
- Molecular Biology
- Proteins
- Enzymology
Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.
- 2 Similar Profiles
Galactokinase
Medicine & Life Sciences
Galactosemias
Medicine & Life Sciences
Galactose
Medicine & Life Sciences
Fasciola hepatica
Medicine & Life Sciences
UDPglucose 4-Epimerase
Medicine & Life Sciences
Enzymes
Medicine & Life Sciences
Proteins
Medicine & Life Sciences
Calmodulin
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Research Output 2007 2019
NAD(P)H quinone oxidoreductase (NQO1): An enzyme which needs just enough mobility, in just the right places
Pey, A. L., Megarity, C. F. & Timson, D. J. 3 Jan 2019 39, 1, BSR20180459Research output: Contribution to journal › Article
Open Access
File
Flavin-Adenine Dinucleotide
NAD
Oxidoreductases
Dicumarol
Quinones
A galactokinase-like protein from the liver fluke Fasciola hepatica
Zinsser, V. L., Cox, C., McAuley, M., Hoey, E. M., Trudgett, A. & Timson, D. J. 21 Jul 2018 192, p. 65-72 8 p.Research output: Contribution to journal › Article
Galactokinase
Fasciola hepatica
Galactose
Acetylgalactosamine
Proteins
Calmodulins from Schistosoma mansoni: biochemical analysis and interaction with IQ-motifs from voltage-gated calcium channels
Thomas, C. M. & Timson, D. 17 May 2018Research output: Contribution to journal › Article
Schistosoma mansoni
Calmodulin
Calcium Channels
Calcium
Ions
Improving the activity and stability of human galactokinase for therapeutic and biotechnological applications
McAuley, M., Mesa-Torres, N., McFall, A., Morris, S., Huang, M., Pey, A. L. & Timson, D. 26 Apr 2018 19, 10, p. 1088-1095 8 p.Research output: Contribution to journal › Article
Galactokinase
Human Activities
Enzyme Replacement Therapy
Enzymes
Galactosemias
Modulation of the mobility of a key region in human galactokinase: Impacts on catalysis and stability
McAuley, M., Huang, M. & Timson, D. J. 19 Sep 2018 81, p. 649-657 9 p.Research output: Contribution to journal › Article
Galactokinase
Catalysis
Enzymes
Galactose
Catalytic Domain
Activities 2004 2017
Higher Education Academy, UK (External organisation)
Timson, D. (Chair)2017 → …
Activity: Membership of professional body
Royal Society of Chemistry (External organisation)
Timson, D. (Chair)2016 → …
Activity: Membership of professional body
Queen's University Belfast
Timson, D. (Visiting researcher)2015 → 2018
Activity: Visiting an external academic institution
Biochemical Society (External organisation)
Timson, D. (Chair)2013 → 2016
Activity: Personal board membership of professional/academic bodies