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Personal profile

Research interests

David Timson is a protein biochemist.  His research focuses on understanding how the structures of proteins influence their functions, with particular relevance to those proteins implicated in human disease and in biotechnology.  Current research areas include:

1.  Proteins of human galactose metabolism and how they are affected by the inherited metabolic disease, galactosemia.

2.  Calcium binding proteins and metabolic enzymes from helminth parasites.

3.  Quinone oxidoreductases

4.  Stress mitigation in biofuel production

5.  The biochemistry underlying fetal alcohol specturm disorders (collaboration led by Prof Paul Gard)

 

Please note:  I have now retired and am unable to undertake active supervision of new projects, since I no longer have a laboratory.  I am happy to advise on these areas and to respond to questions on my papers etc.  This means I am not recruiting postgraduate students or post-docs etc.

Education/Academic qualification

Queen's University Belfast

PhD, University of Birmingham

Bachelor, University of Birmingham

External positions

Editorial Board, Fermentation, MDPI Publishers

Associate Editor, Biosceince Reports, Portland Press

Associate Editor, RSC Advances, Royal Society of Chemistry

Keywords

  • Q Science (General)
  • Biochemistry
  • Molecular Biology
  • Proteins
  • Enzymology

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Research Output

Galactosemia: opportunities for novel therapies

McCorvie, T. J. & Timson, D. J., 19 Feb 2020, Protein Homeostasis Diseases. Pey, A. L. (ed.). Academic Press, p. 221-245 25 p.

Research output: Chapter in Book/Conference proceeding with ISSN or ISBNChapter

  • In Silico Analysis of the Effects of Point Mutations on α-Globin: Implications for α-Thalassemia

    Horri-Naceur, A. & Timson, D. J., 18 May 2020, In : Hemoglobin.

    Research output: Contribution to journalArticle

    Novel and selective inactivators of Triosephosphate isomerase with anti-trematode activity

    Ferraro, F., Corvo, I., Bergalli, L., Ilarraz, A., Cabrera, M., Gil, J., Susuki, B. M., Caffrey, C. R., Timson, D. J., Robert, X., Guillon, C., Freire, T. & Álvarez, G., 13 Feb 2020, In : Scientific Reports. 10, 1, 2587.

    Research output: Contribution to journalArticle

    Open Access
    File
  • Praziquantel: An Enigmatic, Yet Effective, Drug

    Timson, D. J., 26 May 2020, Schistosoma mansoni: Methods and Protocols. Timson, D. J. (ed.). New York, NY: Springer US, p. 1-8 8 p. (Methods in Molecular Biology ; vol. 2151).

    Research output: Chapter in Book/Conference proceeding with ISSN or ISBNChapter

  • Targeting HIF-1α Function in Cancer through the Chaperone Action of NQO1

    Salido, E., Timson, D. J., Betancor-Fernández, I., Palomino-Morales, R. & Pey, A. L., 18 Mar 2020

    Research output: Other contribution

    Open Access
    File

    Activities

    Pharmaceutical Society of Ireland (PSI) (External organisation)

    David Timson (Member)
    2019 → …

    Activity: External boards and professional/academic bodiesPersonal board membership of professional/academic bodies

    PhD external examination

    David Timson (Examiner)
    2017

    Activity: External examination and supervisionResearch degree

    Higher Education Academy, UK (External organisation)

    David Timson (Fellow)
    2017 → …

    Activity: External boards and professional/academic bodiesMembership of professional body

    Royal Society of Chemistry (External organisation)

    David Timson (Fellow)
    2016 → …

    Activity: External boards and professional/academic bodiesMembership of professional body

    Queen's University Belfast

    David Timson (Visiting researcher)
    20152018

    Activity: Visiting positionVisiting an external academic institution