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Personal profile

Research interests

My research interests include the development of novel tools, through the combination of different disciplines in science and engineering, which can aid us in studying the human body and how it is affected by disease, diet, and our environment. 

Current research projects:

  • The development of an analytical probe to monitor the levels of reactive oxygen and nitrogen species in tissues during the progress of tumors and after administration of different therapies.
  • The development of novel 3D-printed materials for various biological applications

Previous research projects:

  • Developing an in vivo method for determining ambient levels of serotonin across brain circuitry at high temporal resolutions
  • Determining differences in serotonergic innervation, modulation, and regulation in various brain regions using fast-scan cyclic voltammetry.

Scholarly biography

I completed my undergraduate degree at the American University of Sharjah, UAE, in 2013 where I earned two Bachelor degrees; Chemistry and Chemical Engineering. I then travelled to the United States to complete my Ph.D. at the University of South Carolina with Dr. Parastoo Hashemi. It is there that I started learning about the complexities of the human mind and how factors like stress and depression can greatly alter the biology of the central nervous system. I became very interested in how we, as scientists, can develop the tools necessary to ask a wide spectrum of questions. During my 5 years in the Hashemi lab, I worked on a wide range of projects including the development of a novel tool to monitor the ambient levels of serotonin in vivo and in real time. Studying the intricacies of serotonin as a neuromodulator and how widely it varies in the brain and under different stressors was a major part of my work, that I accomplished mainly through the use of fast-scan controlled adsorption voltammetry and fast scan cyclic voltammetry .

I am presently a research fellow at the School of Pharmacy and Biomolecular sciences working with Dr. Bhavik Patel and Dr. Melanie Flint.

Education/Academic qualification

PhD, University of South Carolina

1 Aug 20131 Feb 2018

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  • 2 Similar Profiles
Serotonin Medicine & Life Sciences
Conductive materials Chemical Compounds
Electrochemical sensors Chemical Compounds
High performance liquid chromatography Chemical Compounds
Microelectrodes Medicine & Life Sciences
Kynurenine Chemical Compounds
Axons Medicine & Life Sciences
Prefrontal Cortex Medicine & Life Sciences

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Research Output 2016 2019

High performance liquid chromatography
Kynurenine
Metabolism
Tryptophan
Tissue

3D printable conductive materials for the fabrication of electrochemical sensors: A mini review

Bin Hamzah, H., Shafiee, S. A., Abdalla, A. & Patel, B., 13 Sep 2018, In : Electrochemistry Communications. 96, p. 27-31 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Conductive materials
Electrochemical sensors
3D printers
Fabrication
Printing

Voltammetric evidence for discrete serotonin circuits, linked to specific reuptake domains, in the mouse medial prefrontal cortex

West, A., Best, J., Abdalla, A., Nijhout, H. F., Reed, M. & Hashemi, P., 19 Jul 2018, In : Neurochemistry International. 123, p. 50-58 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Prefrontal Cortex
Serotonin
Medial Forebrain Bundle
Norepinephrine Plasma Membrane Transport Proteins
Serotonin Plasma Membrane Transport Proteins

In vivo ambient serotonin measurements at carbon-fiber microelectrodes

Abdalla, A., Atcherley, C., Pathirathna, P., Samaranayake, S., Qiang, B., Peña, E., Morgan, S., Heien, M. & Hashemi, P., 10 Aug 2017, In : Analytical Chemistry. 89, 18, p. 9703-9711 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Microelectrodes
Serotonin
Adsorption
Statistical Models
carbon fiber

Regrowth of Serotonin Axons in the Adult Mouse Brain Following Injury

Jin, Y., Dougherty, S., Wood, K., Sun, L., Cudmore, R., Abdalla, A., Kannan, G., Pletnikov, M., Hashemi, P. & Linden, D., 17 Aug 2016, In : Neuron. 91, 4, p. 748-762 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
Brain Injuries
Axons
Serotonin
Neocortex
Retrograde Degeneration