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Personal profile

Research interests

My research centres on the mechanisms of tumour progression. I am interested in the communication between tumour cells and the cellular components of the tumour microenvironment. My particular interest lies in tumour associated macrophages; I investigate their plasticity, recruitment and the mechanisms they employ to promote tumour growth and metastasis. I have also been investigating TGF-beta induced chemokine and cytokine signalling in epithelial-mesenchymal transition (EMT) and tumour dissemination.

Supervisory Interests

I supervise projects that investigate how macrophages interact with tumour cells and other components of the tumour microenvironment to drive metastatic tumour growth. Tumour associated macrophages are in the forefront of current research because of their ability to enhance tumour survival, invasion, angiogenesis and immune evasion. 

Education/Academic qualification

PhD, Semmelweis University

1 Oct 199431 Aug 1998

Master, Semmelweis University

5 Sep 198831 May 1993

UT MD Anderson Cancer Center

12 Oct 199823 Jul 1999

External positions

Review Editor in Inflammation, Frontiers in Immunology

27 Aug 2018 → …

Keywords

  • RB Pathology
  • cancer
  • tumour associated macrophages
  • inflammation
  • metastasis
  • Q Science (General)
  • chemokines
  • cytokines

Fingerprint Dive into the research topics where Annamaria Gal is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

Macrophages Medicine & Life Sciences
Melanoma Medicine & Life Sciences
Lung Medicine & Life Sciences
CC Chemokines Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Neoplasm Metastasis Medicine & Life Sciences
Chemokine Receptors Medicine & Life Sciences
Cell Communication Medicine & Life Sciences

Research Output 1997 2018

  • 13 Article
  • 4 Abstract
  • 2 Other
  • 1 Conference contribution with ISSN or ISBN

Targeting tumour associated macrophages in anti-cancer therapies

Gal, A., 5 Jan 2018, p. 0-0. 1 p.

Research output: Contribution to conferenceOther

Plasticity of macrophages in the tumour microenvironment

Gal, A., 12 Dec 2017, p. 0-0. 1 p.

Research output: Contribution to conferenceOther

Blocking the recruitment of tumor promoting macrophages leads to resident macrophages modulating the immune response in pulmonary metastasis of melanoma

Gal, A., Tapmeier, T. & Muschel, R., 4 Apr 2016, p. 0-0. 1 p.

Research output: Contribution to conferenceAbstract

Melanoma
Macrophages
Neoplasm Metastasis
Lung
Neoplasms

Comparison of antitumoral and protumoral macrophage migration by targeting differentially regulated chemokine receptors

Wignall, C., Tapmeier, T., Muschel, R. & Gal, A., 15 Jun 2015, p. 0-0. 1 p.

Research output: Contribution to conferenceAbstract

Chemokine Receptors
Macrophages
Neoplasms
Lung
Experimental Melanomas

G-CSF rescues tumor growth and neo-angiogenesis during liver metastasis under host angiopoietin-2 deficiency

Im, J. H., Tapmeier, T., Balathasan, L., Gal, A., Yameen, S., Hill, S., Smart, S., Noterdaeme, O., Kelly, M., Brady, M., Fu, W., Kruse, K., Bernhard, E. J., Augustin, H. G. & Muschel, R., 15 Jan 2013, In : International Journal of Cancer. 132, 2, p. 315-326 12 p.

Research output: Contribution to journalArticle