Centre for Stress and Age-Related Disease

Projects

Projects per year 2002 2017 2018 2028

• 4 Active
• 27 Finished

Projects per year

Search results

• Active

  A biomimetic macromolecular platform for tissue healing and diagnostics at medical device interfaces: a personalised wound dressing model

  Santin, M., Georgoulas, A., Harris, P., Crua, C., Sarker, D., Elsom, J., Sandeman, S., Forss, R., Redhead, L., Terrazzini, N., Saberianpour, S., Melotto, G., Hesketh, A. & Sinha, A.

  EPSRC

  1/06/22 → 31/03/28

  Project: Research Councils / Government Depts.

  • catastrophe 100%
  • petrochemical 91%
  • packaging 91%
  • Tissue 74%
  • Macromolecules 72%

• BioGrOA: Imaging joint biomechanics in growth and osteoarthritis

  Staines, K.

  1/03/22 → 30/09/25

  Project: Research Councils / Government Depts.

  • osteoarthritis 100%
  • biomechanics 50%
  • image analysis 35%
  • medicine 31%
  • joints (animal) 17%

• Drug-eluting in vivo probe to monitor age-related lower bowel dysfunction

  Patel, B. & Yeoman, M.

  EPSRC

  1/01/21 → 30/06/24

  Project: Research Councils / Government Depts.

  • Muscles 100%
  • Feces 56%
  • Equipment and Supplies 49%
  • Mucous Membrane 44%
  • Embarrassment 37%

• Age Concern Eastbourne - The Eastbourne Shed

  Yeoman, M., Flint, M., Trainor, J. & Plumley, O.

  Age Concern, Eastbourne

  1/04/19 → 31/12/23

  Project: Charities

  • health 100%
  • detrimental effects 62%
  • life-span 55%
  • social isolation 46%
  • grant 45%
• Finished

  The impact of psychological stress on cancer burden and recurrence of tubovarian cancer and primary peritoneal cancers

  Flint, M.

  1/08/21 → 10/01/23

  Project: Charities

  • Psychological Stress 100%
  • Recurrence 72%
  • Neoplasms 56%
  • Ovarian Neoplasms 49%
  • Hydrocortisone 48%

• Novel catalytic systems for disposal of the halogenated pharmaceutical and personal care products

  Savina, I.

  Royal Society

  4/11/19 → 3/11/22

  Project: Research Councils / Government Depts.

  • 4-Chlorophenol 100%
  • Meso Porosity 61%
  • Phenol 57%
  • Environment 44%
  • Pharmaceutical 38%

• New avenues for intervention in age-related degenerative disease in the horse: unravelling the role of altered RNA splicing and senescence in tendon

  Faragher, R. & Ostler, L.

  Horserace Betting Levy Board

  3/12/18 → 2/12/21

  Project: Industry

  • tendons 100%
  • horses 50%
  • resveratrol 44%
  • horse diseases 37%
  • RNA splicing 35%

• Extracellular Vesicle Profiling for early detection of leukaemic progression

  Carter, D., Patel, B., Psaila, B., Turner, N. & Zhu, T.

  Cancer Research UK

  1/12/18 → 30/11/19

  Project: Grant

  • Extracellular Vesicles 100%
  • Electrochemistry 23%
  • Dermatoglyphics 16%
  • Oceans and Seas 16%
  • Lipids 9%

• Osteoarthritis: Going back to basics

  Staines, K.

  MRC

  4/09/18 → 3/09/21

  Project: Research Councils / Government Depts.

  • osteoarthritis 100%
  • Osteoarthritis 32%
  • cartilage 22%
  • chondrocytes 19%
  • Musculoskeletal Diseases 6%

• The Application of an Integrative Omics Solution

  Pitsiladis, Y.

  WADA - World Anti-Doping Agency

  1/09/18 → 31/08/20

  Project: Grant

  • multiomics 100%
  • gene expression 53%
  • nationalities and ethnic groups 51%
  • sports 47%
  • normal values 45%

• Physiological Monitoring of Firefighters & Instructors

  Richardson, A., Watkins, E., Watt, P. & Hayes, M.

  Fire Service Trust, Fire Brigades Union, Fire Dept

  1/09/18 → 29/02/20

  Project: Grant

  • Firefighters 100%
  • Hot Temperature 45%
  • Psychology 33%
  • Immunologic Monitoring 29%
  • Physiologic Monitoring 27%

• To determine how polymorphisms in the stress hormone receptor ADRB2 affect treatments in patients with Triple Negative Breast Cancer

  Flint, M.

  Team Verrico

  1/06/18 → 31/07/19

  Project: Grant

  • Adrenergic beta-2 Receptors 100%
  • Triple Negative Breast Neoplasms 95%
  • Hormones 72%
  • Breast Neoplasms 55%
  • Haplotypes 44%

• TNF-Alpha antagonists

  Yeoman, M. & Patel, B.

  BBSRC

  1/04/18 → 31/07/18

  Project: Research Councils / Government Depts.

  • constipation 100%
  • Biomedical Technology Assessment 90%
  • Tumor Necrosis Factor Inhibitors 85%
  • Constipation 73%
  • Elderly 47%

• A reactive oxygen and nitrogen species (ROS/RNS) monitoring system to study their role in cancer

  Flint, M. & Patel, B.

  Cancer Research UK

  1/01/18 → 31/12/19

  Project: Grant

  • neoplasms 100%
  • monitoring 36%
  • drug therapy 28%
  • neoplasm cells 26%
  • cell senescence 21%

• Stress hormones in BRCA mutation carriers increase susceptibility to the development of breast cancer

  Flint, M.

  Breast Cancer Research Trust

  1/12/17 → 30/11/18

  Project: Grant

  • Hydrocortisone 100%
  • DNA Repair 97%
  • DNA Damage 77%
  • Breast Neoplasms 67%
  • Hormones 66%

• GLIOMA: H2020-MSCA-Individual Fellowship - Targeting Glioblastoma using Combinatorial Therapeutic Nanovaccine

  Savina, I., Raveendran, S., Alavijeh, M. & Shevchenko, R.

  Horizon 2020

  2/10/17 → 1/10/19

  Project: Grant

  • glioblastoma 100%
  • chemotherapy 33%
  • delivery 21%
  • hollow 20%
  • gold 17%

• H2020-MSCA-Individual Fellowship- Dual Function Polymer Materials for Blood Contacting Applications

  Sandeman, S. & Azizova, L.

  Horizon 2020

  18/09/17 → 17/09/19

  Project: Grant

  File

  • thrombin 100%
  • immobilization 68%
  • polymers 58%
  • thrombosis 49%
  • Polymers 48%

• Evaluation of faecal pellet sensor device in inflammatory bowel disorder (IBD)

  Patel, B.

  EPSRC

  25/05/17 → 24/01/18

  Project: Research Councils / Government Depts.

  • serotonin 100%
  • pellets 92%
  • animal models 90%
  • dextran sulfate 72%
  • rectum 59%

• Development of a faecal pellet sensor for simultaneous monitoring of luminal signalling and muscle dynamics during defecation

  Patel, B., Yeoman, M. & Covill, D.

  EPSRC

  1/03/17 → 31/08/17

  Project: Research Councils / Government Depts.

  • defecation 100%
  • Serotonin 87%
  • anus 50%
  • rectum 45%
  • Fluoxetine 36%

• DERMA: Design of Enabling-Regenerative Materials (DERMA)

  Allan, I., Santin, M., Gard, P., Sarker, D., Chatterjee, C., Cooper, I., Cragg, P., Otter, S. & Forss, R.

  Interreg VA 2 Seas

  1/09/16 → 31/05/20

  Project: Grant

  • Emulsions 100%
  • Emulsion 86%
  • Surface active agents 72%
  • Poloxamer 68%
  • Nanoparticles 59%

• Interaction between sensory and supporting cells in the organ of Corti: basis for sensitivity and frequency selectivity of mammalian cochlea

  Lukashkin, A., Russell, I., Lukashkina, V. & Simoes, P.

  MRC

  1/09/15 → 31/08/20

  Project: Grant

  • hairs 100%
  • hearing 67%
  • cells 44%
  • genetic disorders 25%
  • extracellular matrix 11%

• CARBALIVE

  Sandeman, S.

  1/05/15 → 31/01/21

  Project: Grant

  • Liver Diseases 100%
  • Fatty Liver 79%
  • Bacterial Translocation 79%
  • Carbon 58%
  • Liver Cirrhosis 54%

• Antipsychotics and beta cell toxicity

  Bone, A., Gaffar, F., Gebrekirstos, T., Kumar, S., Macfarlane, W., Scutt, G. & Honey, M.

  1/01/14 → 31/12/17

  Project: Research

  • Olanzapine 100%
  • Antipsychotic Agents 75%
  • TOR Serine-Threonine Kinases 45%
  • Glucose 38%
  • Schizophrenia 33%

• Electrochemical sensor for monitoring levels of oxygen and nitrogen reactive species to benefit ageing research

  Patel, B., Yeoman, M. & Faragher, R.

  1/04/13 → 31/03/14

  Project: Research Councils / Government Depts.

  • microelectrodes 100%
  • Glucocorticoids 78%
  • Hydrocortisone 76%
  • DNA Damage 75%
  • carbon nanotubes 74%

• SensoPellet: A new tool to investigate signalling and motility in the lower digestive tract

  Patel, B.

  EPSRC

  1/05/12 → 30/06/13

  Project: Research Councils / Government Depts.

  • pellets 100%
  • serotonin 90%
  • sensors (equipment) 70%
  • defecation 47%
  • monitoring 35%

• Flax – Increasing its Value for Society

  Mikhalovsky, S., Farrer, J., Bowyer, C., Watt, C., Allan, I., Mikhalovska, L. & Cragg, P.

  1/01/12 → 30/06/15

  Project: EU / International

  • luxury 100%
  • flax 90%
  • sustainability 60%
  • production method 29%
  • industrial production 28%

• Cell Isolation

  Yeoman, M., Patel, B. & Fidalgo, S.

  BBSRC

  1/08/11 → 31/07/14

  Project: Research Councils / Government Depts.

  • Enterochromaffin Cells 100%
  • Mucous Membrane 26%
  • Cell Separation 19%
  • Gastrointestinal Tract 14%
  • Colon 13%

• OncoNanoBBB

  Savina, I., Mikhalovsky, S., Mikhalovska, L. & Illsley, M.

  1/01/11 → 31/12/15

  Project: Research

  • Nanoparticles 100%
  • Blood-Brain Barrier 81%
  • Pharmaceutical Preparations 46%
  • Technology 46%
  • Molecular Imaging 33%

• Antidepressants in Older People

  Yeoman, M., Scutt, G., Overall, A., Patel, B., Scott, R., Wright, J. & Hachoumi, L.

  NIHR

  1/09/10 → 31/03/16

  Project: Grant

  • Citalopram 100%
  • Genotype 80%
  • Aged, 80 and over 78%
  • Major Depressive Disorder 54%
  • Antidepressive Agents 45%

• Integrated analysis of the impact of age-associated neuronal and enteroendocrine changes on normal bowel functions

  Yeoman, M., Patel, B., Saffrey, J. & Ranson, R.

  BBSRC

  1/10/09 → 31/12/12

  Project: Research Councils / Government Depts.

  • colon 100%
  • mice 80%
  • Anal Canal 71%
  • Interstitial Cells of Cajal 66%
  • Nerve Fibers 60%

• Cumulative and temporal analysis of multiple co-released neurotransmitters.

  Yeoman, M.

  EPSRC

  1/10/02 → 30/09/05

  Project: Research Councils / Government Depts.

  File

  • Neurotransmitter Agents 100%
  • Serotonin 97%
  • Snails 93%
  • Nitric Oxide 77%
  • Nervous System 62%