Organization profile

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The Centre for Stress and Age-Related Disease comprises internationally recognised researchers that work on multidisciplinary projects at the biology-chemistry interface, to understand the role played by stress in the initiation and progression of age-related disease and to improve health and wellbeing in older people.

 The centre is unique in the UK; it has scientific expertise in examining the impact that a range of stressors (psychological, xenobiotic, oxidative and mechanical) have on the initiation and progression of age-related disease.

 Research takes advantage of the multi- and inter-disciplinary academic staff, with much of our research being conducted at the biology/chemistry interface, generating novel datasets and attracting significant  funding.

 A multidisciplinary approach allows us to not only understand the involvement of a range of stressors in disease initiation and progression but also allows us to develop novel ways of diagnosing and preventing disease. Our members collaborate locally, nationally and internationally with other academic institutions, charities, hospitals and businesses.

Our work focuses on three main areas of research: Chemical Biology, Cell Biology and Translational Science.

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Fingerprint The fingerprint is based on mining the text of the scientific documents related to the associated persons. Based on that an index of weighted terms is created, which defines the key subjects of research unit

Chemical Warfare Agents Chemical Compounds
Serotonin Medicine & Life Sciences
Hot Temperature Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Nitric Oxide Synthase Medicine & Life Sciences
Nitric Oxide Medicine & Life Sciences
Soman Chemical Compounds
Proteins Medicine & Life Sciences

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Projects 2015 2020

Research Output 2017 2019

Direct oral anticoagulant (DOAC)-mediated vasodilation: Role of nitric oxide

Mabley, J., Patel, J., Sayed, A., Arya, R. & Scutt, G., 12 Feb 2019, In : Thrombosis Research. 176, p. 36-38 3 p.

Research output: Contribution to journalLetterResearchpeer-review

Nitric Oxide
Vitamin K
Food-Drug Interactions

Exercise Induced cardiac troponin elevation: An update on the evidence, mechanism and implications

Baker, P., Leckie, T., Harrington, D. & Richardson, A., 14 Mar 2019, In : International Journal of Cardiology: Heart & Vasculature. 22, p. 181-186 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
Chest Pain
Acute Coronary Syndrome
Decision Making

Fructose 1,6-bisphosphatase: getting the message across

Timson, D., 6 Mar 2019, In : Bioscience Reports. 39, 3, p. 1-5 5 p., BSR20190124.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
Adenosine Monophosphate
Binding Sites
Allosteric Regulation

Activities 1996 2019

Frontiers in Immunology (Journal)

Nadia Terrazzini (Reviewer)
21 Jan 2019

Activity: Publication peer-review and editorial workPublication Peer-review

Centre for Stress and Age-Related Disease Outreach Event

Mark Yeoman (Participant)
4 Apr 2019

Activity: EventsOutreach and Public Engagement

Is impaired mucosal signalling responsible for age-related changes in lower bowel function

Mark Yeoman (Presenter)
30 Jan 2019

Activity: External talk or presentationInvited talk