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The Centre for Stress and Age-Related Disease comprises internationally recognised researchers that work on multidisciplinary projects at the biology-chemistry interface, to understand the role played by stress in the initiation and progression of age-related disease and to improve health and wellbeing in older people.

 The centre is unique in the UK; it has scientific expertise in examining the impact that a range of stressors (psychological, xenobiotic, oxidative and mechanical) have on the initiation and progression of age-related disease.

 Research takes advantage of the multi- and inter-disciplinary academic staff, with much of our research being conducted at the biology/chemistry interface, generating novel datasets and attracting significant  funding.

 A multidisciplinary approach allows us to not only understand the involvement of a range of stressors in disease initiation and progression but also allows us to develop novel ways of diagnosing and preventing disease. Our members collaborate locally, nationally and internationally with other academic institutions, charities, hospitals and businesses.

Our work focuses on three main areas of research: Chemical Biology, Cell Biology and Translational Science.

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Fingerprint Dive into the research topics where Centre for Stress and Age-Related Disease is active. These topic labels come from the works of this organisation's members. Together they form a unique fingerprint.

Chemical Warfare Agents Chemical Compounds
Serotonin Medicine & Life Sciences
Hot Temperature Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Nitric Oxide Synthase Medicine & Life Sciences
Nitric Oxide Medicine & Life Sciences
Soman Chemical Compounds
Pharmaceutical Preparations Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2015 2020

Research Output 2017 2019

Direct oral anticoagulant (DOAC)-mediated vasodilation: Role of nitric oxide

Mabley, J., Patel, J., Sayed, A., Arya, R. & Scutt, G., 12 Feb 2019, In : Thrombosis Research. 176, p. 36-38 3 p.

Research output: Contribution to journalLetterResearchpeer-review

Vasodilation
Anticoagulants
Nitric Oxide
Vitamin K
Food-Drug Interactions

Drug diffusion along an intact mammalian cochlea

Sadreev, I. I., Burwood, G. W. S., Flaherty, S. M., Kim, J., Russell, I. J., Abdullin, T. I. & Lukashkin, A. N., 26 Apr 2019, In : Frontiers in Cellular Neuroscience. 13, 161.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Cochlea
Salicylates
Pharmaceutical Preparations
Perilymph
Membranes

Exercise Induced cardiac troponin elevation: An update on the evidence, mechanism and implications

Baker, P., Leckie, T., Harrington, D. & Richardson, A., 14 Mar 2019, In : International Journal of Cardiology: Heart & Vasculature. 22, p. 181-186 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Troponin
Exercise
Chest Pain
Acute Coronary Syndrome
Decision Making

Activities 1996 2019

Is impaired mucosal signalling responsible for age-related changes in lower bowel function

Mark Yeoman (Presenter)
30 Jan 2019

Activity: External talk or presentationInvited talk

Alzheimer's Research UK

Mark Yeoman (Participant)
31 Jan 2019

Activity: EventsOutreach and Public Engagement

Centre for Stress and Age-Related Disease Outreach Event

Mark Yeoman (Participant)
4 Apr 2019

Activity: EventsOutreach and Public Engagement