Applied Biosciences Research and Enterprise Group

Organization profile

Profile Information

The Applied Biosciences Research and Enterprise Group encompasses a broad range of multidisciplinary research interests including protein biochemistry and biotechnology, medical microbiology, mechanisms of disease and education for promotion of health and wellbeing.

The group has access to state-of-the-art facilities and is comprised of experienced academics, early career researchers and students working within and beyond the School of Pharmacy and Biomolecular Sciences with national and international collaborators of industry, healthcare and academia to boost research potential and translational impact.

Current specific research investigates the proteins from pathogens, focussing on calcium binding proteins, metabolic enzymes and cytoskeletal components, the engineering of enzymes for biocatalytic purposes, especially sugar kinases and oxidoreductases, the microbial stress biochemistry, including applications to biofuels, the mycobiome of chronic wounds and its impact on wound healing, the epidemiology of unusual and endemic neglected fungal diseases, the diagnostics and point-of-care testing in microbiology, the cryopreservation of articular cartilage, aiming to advance osteoarthritis treatment, the cellular mechanisms of bone lengthening, the role of small non-coding microRNAs in osteosarcoma, and the tumour microenvironment, including the intercellular communication between tumour associated macrophages, cancer associated fibroblasts and tumour cells. Additional research covers the development of learning and teaching strategies and education interventions, for example addressing organ donation and transplantation, to empower student learners, foster inclusive practice, and promote the health and wellbeing of the community.

Fingerprint Dive into the research topics where Applied Biosciences Research and Enterprise Group is active. These topic labels come from the works of this organisation's members. Together they form a unique fingerprint.

Galactokinase Medicine & Life Sciences
Praziquantel Medicine & Life Sciences
Schistosoma mansoni Medicine & Life Sciences
Enzymes Medicine & Life Sciences
Galactosemias Medicine & Life Sciences
Calcium Channels Medicine & Life Sciences
Proteins Medicine & Life Sciences
Galactose Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2018 2020

EF Hand Motifs
Schistosoma mansoni
Ion Channels
Protein Binding

A Dynamic Core in Human NQO1 Controls the Functional and Stability Effects of Ligand Binding and Their Communication across the Enzyme Dimer

Vankova, P., Salido, E., Timson, D., Man, P. & Pey, A. L., 12 Nov 2019, In : Biomolecules. 9, 11, 728.

Research output: Contribution to journalArticle

Open Access
Flavin-Adenine Dinucleotide

Dynamic origins of substrate promiscuity in bacterial galactokinases

McAuley, M., Huang, M. & Timson, D., 17 Oct 2019, In : Carbohydrate Research. 486, 107839.

Research output: Contribution to journalArticle

Escherichia coli
Sugar Phosphates
Bacterial Structures

Activities 2004 2017

PhD external examination

David Timson (Examiner)

Activity: External examination and supervisionResearch degree

Higher Education Academy, UK (External organisation)

David Timson (Fellow)
2017 → …

Activity: External boards and professional/academic bodiesMembership of professional body

Royal Society of Chemistry (External organisation)

David Timson (Fellow)
2016 → …

Activity: External boards and professional/academic bodiesMembership of professional body